Endocrine Abstracts

Introduction: Detection of TSH-receptor autoantibodies in the diagnosis of graves disease is well established. however these autoantibodies may not be always present in some forms of correctly observed autoimmune hyperthyroidism. Here, we describe a patient with hyperthyroid Graves’ disease without detectable thyrotropin receptor antibodies.Case report: She was A 55-year-old woman, presented with a 2 years history of increased sweating, palpitations...

Introduction: The classical revealing manifestations of a pituitary adenoma are represented by the combination of a tumor syndrome and endocrine syndrome. The occurrence of meningoencephalitis as a mode of revelation of a macroadenoma is exceptional.Case: Mr. M.O, 36 years old, with no significant medical history, brutally presented severe headaches, vomiting, behavioral disorder with fever and bilateral decreased visual acuity. On examination, the patie...

Introduction: Latent autoimmune diabetes in adults (LADA) is an endocrine disorder characterized by a progressive destruction of pancreatic beta cells by an autoimmune mechanism leading to absolute insulin deficiency. However, recent studies have shown the presence of a certain degree of insulin resistance in LADA patients, hence the possibility of the existence of a metabolic syndrome in these patients. The purpose of our work is to evaluate the presence of metabolic syndrome...

Introduction: Neuroendocrine tumors are rare tumors with increasing incidence. They are characterized by the expression of proteins and hormonal products common to neurons and endocrine cells, and are often diagnosed at an advanced stage due to the delayed onset of nonspecific symptoms. We report the case of a patient who presented with a flush syndrome associated with a thyroid nodule and who was subsequently diagnosed with a digestive neuroendocrine tumor<p class="abstex...

Introduction: Vitamin D deficiency is a health problem related to cardiovascular diseases, autoimmune diseases and cancers. Several studies have shown a significant prevalence of vitamin D deficiency in T1D with positive impact of supplementation on glycemic control. The objective of our work is to evaluate vitamin D status in our T1D patientsPatients and methods: Our study has included 35 patients followed for T1D, vitamin D status was ordered in all pa...

Introduction: Subcutaneous calcinosis are deposits of hydroxyapatite crystals in the skin. They are hard masses, poorly organized, located most often in the dermis or hypodermis. They are secondary to either local tissue alterations or the penetration of calcium salts into the skin, or to an abnormal phosphocalcic metabolism but which remains an exceptional complication in case of primary hyperparathyroidism. We report the case of a patient admitted to the endocrinology depart...

Introduction: The discovery of a pheochromocytoma during pregnancy is very rare. The diagnostic and therapeutic approach determines the maternal and fetal prognosis. We present the case of a pheochromocytoma discovered during a pregnancy of 16 weeks of amenorrhea.Case report: Mrs. A.H 29 years old, primigravida, presented at 6 weeks of amenorrhea with hypertension, she was treated by alpha methyl dopa 500mg and nicardipne 20 mg; at 16 weeks she was hospi...

Introduction: The discovery of a pheochromocytoma during pregnancy is very rare. The diagnostic and therapeutic approach determines the maternal and fetal prognosis. We present the case of a pheochromocytoma discovered during a pregnancy of 16 weeks of amenorrhea.Case report: Mrs. A.H 29 years old, primigravida, presented at 6 weeks of amenorrhea with hypertension, she was treated by alpha methyl dopa 500mg and nicardipne 20mg; at 16 weeks she was hospit...

Introduction: When hypoglycemia is deep and repeated, it can induce various neurological disorders, including epileptic seizures. The link between hypoglycemia and epileptic phenomena is complex and poorly explained. We report 3 cases of epilepsy induced by repeated episodes of deep hypoglycemia.Cases report: Mr D.M, 48 years old, with a history of 3 episodes of hypoglycemic coma, admitted for status epilepticus with a blood glucose level of 0.4 g/l; cer...

Introduction: Congenital idiopathic hypogonadotropic hypogonadism is a rare genetic disorder caused by an isolated defect in GnRH secretion by the hypothalamus or, less frequently, by a defect in the action of GnRH on pituitary gonadotropes. The majority of cases are sporadic but there are also family forms. We report a case of one family.Case report: These are 2 brothers with a family history of primary infertility in the maternal uncle. An 18-year-old ...